Jack Mellor

Jack Mellor

Jack Mellor graduated from the University of Cambridge in 1995 with a degree in Neurophysiology and remained in Cambridge to pursue a PhD on the biophysics and pharmacology of inhibitory synaptic transmission at the MRC Laboratory of Molecular Biology under the supervision of Andrew Randall. After completing graduate studies in 1998, Jack Mellor briefly worked on science policy for the UK government before joining Roger Nicoll’s laboratory at the University of California, San Francisco, where the research focused on the mechanisms of synaptic plasticity in the hippocampus. In 2002, Jack Mellor returned to the UK to join John Isaac’s laboratory at the University of Bristol before establishing an independent research group in 2004 with an MRC-funded Career Development Fellowship. Currently, Jack Mellor leads a research team that collaborates extensively with academic, clinical, and industry partners. The team's work focuses on how hippocampal network function is influenced by synaptic plasticity and neuromodulators, as well as how these processes are disrupted in psychiatric and neurological disorders, leading to impairments in cognition.